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Hydrocodone is a potent drug that helps in the treatment of pain which vary from moderate to severe. This combination medication is used to relieve moderate to severe pain. It contains an opioid(narcotic) pain reliever (hydrocodone) and a non-opioid pain reliever (acetaminophen).

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Inform your doctor at once if you have any serious side effects, including: mental/mood changes (such as agitation, confusion, hallucinations), stomach/abdominal pain, difficulty urinating, signs of your adrenal glands not working well (such as loss of appetite, unusual tiredness, weight loss).

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Hydrocodone is a codeine synthetic opioid. It is widely used to control mild to extreme pain in combination with acetaminophen. Historically, hydrocodone was used as a cough substrator, but in modern cough and cold formulations this was mainly replaced by dextromethorphan. Hydromorphone has since been extensively used as an analgesic as the main metabolite of hydrocodone and is typically used in extreme pain. Hydrocodone was originally approved for use by the fda in the march 1943 cough suppressant hycodan syrup.

Indications:

Hydrocodone in conjunction with acetaminophen and ibuprofen, and in conjunction with decongestants, antihistamines and expectorants, has been recommended for prevention of severe discomfort, as well as the symptomatic treatment of common rhinoid and allergy rhinitis.

Hydrocodone can also be similar to other opioids in the brain to various acts. Activating the periaqueductal gray mor prevents the medulo-spinal neuron gabaergic sound. This helps these neurons, which migrate into the dorsal horn of the backbone, to deter pain sensing by stimulating inhibitory interneurons in secondary afferents. Gabaergic neurons can also be blocked in the ventral tegmental region by more